A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration.

This work aims to design a synthetic construct that mimics the natural bone extracellular matrix through innovative approaches based on simultaneous type I collagen electrospinning and nanophased hydroxyapatite (nanoHA) electrospraying using non-denaturating conditions and non-toxic reagents. The morphological results, assessed using scanning electron microscopy and atomic force microscopy (AFM...

متن کامل

Development of a Collagen-Nanohydroxyapatite Gene Activated Matrix for Bone Tissue Regeneration

Galway, Ireland Development of a Collagen-Nanohydroxyapatite Gene Activated Matrix for Bone Tissue Regeneration Gráinne M Cunniffe, 2 Glenn R Dickson R, Sonia Partap, Garry P Duffy, Fergal J O’Brien, Corresponding Author: [email protected] School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, N. Ireland. Department of Anatomy, Royal College of Surgeons, Dublin, Irela...

متن کامل

Development of Novel Biocomposite Scaffold of Chitosan-Gelatin/Nanohydroxyapatite for Potential Bone Tissue Engineering Applications

In this study, a three-dimensional chitosan-gelatin/nanohydroxyapatite (ChG/nHaP) scaffold was successfully fabricated and characterized in terms of swelling, degradation, cell proliferation, cell attachment, and mineralization characterizations. The ChG/nHaP scaffold was fabricated with a mean pore size of 100-180 μm. Our results showed that the physicochemical and biological properties of the...

متن کامل

Collagen for bone tissue regeneration.

In the last decades, increased knowledge about the organization, structure and properties of collagen (particularly concerning interactions between cells and collagen-based materials) has inspired scientists and engineers to design innovative collagen-based biomaterials and to develop novel tissue-engineering products. The design of resorbable collagen-based medical implants requires understand...

متن کامل

Combinatorial gene therapy accelerates bone regeneration: non-viral dual delivery of VEGF and BMP2 in a collagen-nanohydroxyapatite scaffold.

Vascularization and bone repair are accelerated by a series of gene-activated scaffolds delivering both an angiogenic and an osteogenic gene. Stem cell-mediated osteogenesis in vitro, in addition to increased vascularization and bone repair by host cells in vivo, is enhanced using all systems while the use of the nanohydroxyapatite vector to deliver both genes markedly enhances bone healing.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biofabrication

سال: 2014

ISSN: 1758-5082,1758-5090

DOI: 10.1088/1758-5082/6/3/035015